Presentation Information

Inside Out: Unraveling the Dance of NeoHormones, the Estrobolome, and the Microbiome

• Speaker: Laurel A. Wilson , IBCLC, BSc, CLE, CLD, CCCE, CLSP
• Presentation Type:
• Duration: 60 Mins
• Credits: 1 CERP, 1 Nursing CEU, 1 CME, 0.1 Midwifery CEU, 1 Dietetic CEU

Abstract:

The remarkable process by which mammals produce and provide nourishment to their young through milk, is regulated by a complex interplay of hormones and intricate biological mechanisms. Recently, emerging research has shed light on the significant role of neohormones in the evolution of mammalian reproduction and lactation. Neohormones and their interaction with the estrobolome—a collection of gut bacteria involved in the metabolism of estrogen compounds, are yet another important component that can potentially impact successful lactation. This abstract aims to explore the fascinating relationship between lactation, neo-hormones, and the estrobolome. We will delve into pivotal neohormones, oxytocin, relaxin and estrogen and their potential impact on lactation. We explore the estrobolome, a dynamic consortium of gut bacteria involved in the metabolism of estrogen compounds. Recent studies have revealed the estrobolome's intricate relationship with overall health, particularly in modulating estrogen levels and influencing hormonal balance. We examine the possible connection between the estrobolome and lactation, investigating whether the composition and activity of gut bacteria may impact lactation outcomes. Lastly, we consider the how the exposome (environmental influences) shapes lactation, neo-hormones, and the estrobolome. Understanding the interplay between these elements can inform strategies to optimize lactation outcomes, enhance maternal/parental-infant health, and provide valuable insights into therapeutic interventions for lactation-related challenges. In conclusion, this abstract underscores the significance of exploring the relationship between lactation, neo-hormones, and the estrobolome. By unraveling the complex mechanisms at play, we can deepen our understanding of lactation processes, shed light on the effects of neo-hormones, and illuminate the potential role of the estrobolome in modulating lactation outcomes. Ultimately, this knowledge may contribute to improved health and well-being for lactating individuals and their offspring.